Which of the following may be caused in part by a deficiency in folic acid, a B-vitamin present in green leafy vegetables, dried beans, liver, orange juice, and grapefruit juice? 1) Phenylketonuria and hypothyroidism 2) German Measles (Rubella) 3) Tay-Sachs disease and Down Syndrome 4) Anencephaly and Spina Bifida
